nav emailalert searchbtn searchbox tablepage yinyongbenwen piczone journalimg searchdiv qikanlogo popupnotification paper
2024 03 v.34 6-9
气相色谱法测定聚乙二醇200中乙二醇、二甘醇、三甘醇和四甘醇含量
基金项目(Foundation):
邮箱(Email): 8185890@qq.com;
DOI:
中文作者单位:

青岛市产品质量检验研究院;

摘要(Abstract):

建立气相色谱-氢离子火焰测定聚乙二醇200中乙二醇、二甘醇、三甘醇和四甘醇的测定方法。用一级水将聚乙二醇200稀释后直接测定,前处理操作简单。结果显示,乙二醇、二甘醇、三甘醇和四甘醇在测定浓度范围内线性良好,线性相关系数均大于0.99,回收率分别为93.9%~116.9%,平均相对标准偏差(RSD)为0.19%~1.40%。该方法简单、快速、准确,可以满足聚乙二醇200中乙二醇、二甘醇、三甘醇和四甘醇测定的需要。

关键词(KeyWords): 气相色谱-火焰离子检测器;聚乙二醇200;乙二醇;二甘醇;三甘醇;四甘醇
参考文献

[1]周小华,庞文倩,赵恂,等.HPLC测定聚乙二醇中乙二醇、二甘醇和三甘醇[J].中国药学杂志,2021,56(8):682-687.ZHOU X H,PANG W Q,ZHAO X.et al.Simultaneous determination of ethylene glycol,diethylene glycol and ttriethylene glycol in polyethylene glycol by HPLC[J].Chin Pharm J,2021,56(8):682-687.(in Chinese)

[2]李莉,李硕,李祥胜,等.气相色谱法测定化妆品中的乙二醇和二甘醇[J].香料香精化妆品,2019,(1):42-46.LI L,LI S,LI X S,et al.Determination of ethylene glycol and diethylene glycol in cosmetics by gas chromatography[J].Flavour Fragrance Cosmetics,2019,(1):42-46.(in Chinese)

[3] GB/T 22114—2021牙膏用保湿剂甘油和聚乙二醇[S].

[4] GB 1886.302—2021食品安全国家标准食品添加剂聚乙二醇[S].

[5]雷雅娟,熊晔蓉,朱颜玥,等.气相色谱法测定泊洛沙姆188中乙二醇、二甘醇和三甘醇含量[J].中国药科大学学报,2019,50(6):694-698.LEI Y J,XIONG Y R,ZHU Y Y,et al. Determination of ethylene glycol,diethylene glycol and triethylene glycol in poloxamer 188 by gas chromatography[J].China Pharm Univ,2019,50(6):694-698.(in Chinese)

[6]李浩宇,唐宝强,何东升,等.气相色谱法测定药用辅料聚西托醇1000种的残留杂质[J].中国药科大学学报,2022,53(3):293-299.LI H Y,TANG B Q,HE D S,et al.Determination of residual impurities in pharmaceutical excipient ceto-macrogol1000 by gas chromatography[J].China Pharm Univ,2022,53(3):293-299.(in Chinese)

[7]谢华萍,邓双炳,魏勇翔,等.气相色谱内标法测定注射级聚山梨酯80中乙二醇、二甘醇、三甘醇残留量[J].药品评价,2022,19(11):663-666.XIE H P,DENG S B,WEI Y X,et al.Determination of glycol,diglycol and trithylene glycol residues in injectiongrade polysorbate 80 by gc internal standard method[J].Drug Evaluation,2022,19(11):663-666.(in Chinese)

[8]郜淑晓,祝颂,赵恂,等.聚氧乙烯中乙二醇和二甘醇残留的HPLC和GC测定法比较研究[J].药物分析杂志,2020,40(10):1820-1827.GAO S X,ZHU S,ZHAO X,et al.Comparative study on HPLC and GC methods for determination of ethylene glycol and diethylene glycol residues in polyethylene oxide[J].Chin J Pharm Anal,2020,40(10):1820-1827.(in Chinese)

[9]黄毅,李利伟,高万杰,等.GC-FID测定聚乙二醇中乙二醇和二甘醇的含量[J].口腔护理用品工业,2016,26(6):15-17.HUANG Y,LI L W,GAO W J,et al. Determination of ethylene glycol and diethylene glycol in polyethylene glycol by GC-FID[J].Oral Care Industry,2016,26(6):15-17.(in Chinese)

基本信息:

DOI:

中图分类号:TQ317;O657.71

引用信息:

[1]孔祥祥,李建兵,陈东等.气相色谱法测定聚乙二醇200中乙二醇、二甘醇、三甘醇和四甘醇含量[J].质量安全与检验检测,2024,34(03):6-9.

基金信息:

检 索 高级检索

引用

GB/T 7714-2015 格式引文
MLA格式引文
APA格式引文